The purpose of this study was to update the management of invasive cervical\ncancers diagnosed during pregnancy. Patients and methods: This study was\nperformed retrospectively at radiotherapy department of National Institute of\nOncology Rabat Morocco. From 01/04/2005 to 31/05/2010, ten patients with\ninvasive cervical cancer during pregnancy were included. Results: Ten patients\nwere included in the study. The staging was as follow: stage IIIB (n = 4);\nstage IIB (n = 2) and stage IB2 (n = 4). The radical abdominal hysterectomy\nwith pelvic lymphadenectomy was performed in five patients; a therapeutic\ninterruption of pregnancy was performed in four patients. One pregnancy has\nresulted in the birth of a living child (by cesarean section). Adjuvant treatment\nwas concomitant chemoradiotherapy followed by low dose rate (LDR)\nbrachytherapy in three patients; adjuvant concomitant chemoradiotherapy\nfollowed by high dose rate (HDR) brachytherapy was performed in four patients;\na HDR brachytherapy was done in one patient. Two patients have received\nan exclusive external radiotherapy. After a median follow-up of 4 years\n(2 - 7 years), there were bone and lung metastases in one patient. Nine patients\nare alive after completed treatment. Conclusion: Our series focused on\nten patients with invasive cervical cancer during pregnancy. Management is\ncomplex and requires discussion in a multidisciplinary meeting. Routine\nscreening of cervical cancer and awareness are the key point to improve the\ntreatment and survival rate of patients. The management of all cases is according\nto international recommendations.
Loading....